Zolpidem Tartrate and Somnambulism
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Mouth Dissolving Tablet of Zolpidem Tartrate
Conventional solid dosage form suffers from problem like difficulty in swallowing with age, onset of action and physiological factor of patient like gastric emptying time. To overcome this mouth dissolving tablet is a newer approach to drug delivery. Zolpidem is preferentially used for the short term treatment of insomnia. The aim of present study is to formulate and evaluate mouth dissolving t...
متن کاملFormulation and Evaluation of Extended- Release Tablet of Zolpidem Tartrate by Wet Granulation Technique
The goal of this study was to design and evaluate extended - release system of the hypnotic agent, Zolpidemtartrate usefulness for the treatment of insomnia. The half-life of this drug is about 1.9 - 3 hours that indicatingit a candidate for the extended release formulation. Our investigation relates to development of extendeddrug delivery system based on Hydroxy propyl methyl cellulose (HPMCK4...
متن کاملSomnambulism
In sound sleep, all the functions of the brain and spinal cord except those connected with the maintenance of life itself are in abeyance. The order in which the various functions are lost is : (i) loss of the higher mental faculties, (2) of the motor functions, relaxation of muscles, and (3) loss of common sensation and of the special senses. They are awakened in the reverse order: the sensory...
متن کاملFormulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique
The present investigation describes the influence of the concentration of PEG 6000 as a melt binder and ratio of HPMC K4M : PVP on Zolpidem tartrate controlled-release tablet formulations using 3(2) full factorial design. The ratio of HPMC K4M and PVP K30 (X(1)) and the concentration of melt binder (X(2)) were selected as independent variables, and drug release at 1 hr (Q(1)), 4 hr (Q(4)), 8 hr...
متن کاملFormulation and Evaluation of Mouth Dissolving Films of Zolpidem Tartrate by Exploration of Polymers Combination
Fast dissolving drug delivery is the new approach to administer drugs; mouth dissolving film is one of them. The object of the present research work was to formulate a mouth dissolving film of Zolpidem tartrate from polymers Hydroxypropyl cellulose (EF-P) with a combination of Hydroxypropyl methyl cellulose K-15 by solvent casting method for enhancing the drug release rate and absorption to inc...
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ژورنال
عنوان ژورنال: Military Medicine
سال: 1999
ISSN: 0026-4075,1930-613X
DOI: 10.1093/milmed/164.9.669